Fluoroquinolone restriction to control fluoroquinolone-resistant Clostridium difficile
نویسندگان
چکیده
منابع مشابه
gyrA Mutations in Fluoroquinolone-resistant Clostridium difficile PCR-027
gyrA Mutations in Fluoroquinolone-resistant Clostridium difficile PCR-027 To the Editor: Clostridium diffi-cile is the most common cause of bacterial diarrhea in hospitalized patients (1). Antimicrobial drug therapy is the most important risk factor associated with the acquistion of C. difficile, and several antimicrobial agents including clindamycin, amoxicillin, and cepha-lo-sporins have been...
متن کاملNational antimicrobial stewardship and fluoroquinolone-resistant Clostridium difficile in China
php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, p...
متن کاملFluoroquinolone Resistance and Clostridium difficile, Germany
We characterized 670 Clostridium difficile isolates collected from patients in 84 hospitals in Germany in 2008. PCR ribotyping showed high prevalence of ribotype 001 and restricted dissemination of ribotype 027 strains. Fluoroquinolone resistance and associated gyrase mutations were frequent in various ribotypes, but no resistance to metronidazole or vancomycin was noted.
متن کاملFluoroquinolone Use and Clostridium difficile–Associated Diarrhea
We performed a case-control study to evaluate the association between antibiotic use and Clostridium difficile-associated diarrhea (CDAD), matching for admission unit and time at risk for CDAD. A multivariable regression model showed that treatment with fluoroquinolones (odds ratio 12.7; 95% confidence interval 2.6 to 61.6) was the strongest risk factor for CDAD.
متن کاملEmergence and control of fluoroquinolone-resistant, toxin A-negative, toxin B-positive Clostridium difficile.
BACKGROUND Clostridium difficile is a major cause of infectious diarrhea in hospitalized patients. Between August 2003 and January 2004, we experienced an increase in the incidence of C. difficile-associated disease. We describe the investigation into and management of the outbreak in this article. METHODS A total of 73 consecutive patients with nosocomial C. difficile-associated diarrhea wer...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Lancet Infectious Diseases
سال: 2017
ISSN: 1473-3099
DOI: 10.1016/s1473-3099(17)30052-x